Contraction of reconstituted Dictyostelium cytoskeletons: an apparent role for higher order associations among myosin filaments.


A large number of cellular functions require assembly of actin and myosin and coordinated interactions between the resulting filaments. To better understand the structure and function of one such contractile assembly, we have begun fractionation and reconstitution studies of Dictyostelium cytoskeletons. Isolated cytoskeletons rapidly contracted when mixed… (More)


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