Contraction of isolated smooth-muscle cells--structural changes.

  title={Contraction of isolated smooth-muscle cells--structural changes.},
  author={Fredric S. Fay and C M Delise},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={70 3},
The contraction of isolated smooth-muscle cells has been correlated with evagination of the cell membrane, a marked change in myofilament orientation, and a decrease in cellular volume. Both localized and full contractions have been elicited in the same cell by varying the intensity of electrical stimulation. These results may be explained by a model of the smooth-muscle cell in which the contractile apparatus extends between attachment sites on the cell membrane that are relatively closely… CONTINUE READING