Contraction of human brain endothelial cells induced by thrombogenic and fibrinolytic factors. An in vitro cell culture model.

@article{Nagy1995ContractionOH,
  title={Contraction of human brain endothelial cells induced by thrombogenic and fibrinolytic factors. An in vitro cell culture model.},
  author={Zolt{\'a}n Zsolt Nagy and Krasimir Kolev and Eva Csonka and M P{\'e}k and Raymund Machovich},
  journal={Stroke},
  year={1995},
  volume={26 2},
  pages={265-70}
}
BACKGROUND AND PURPOSE Vasogenic brain edema is a frequent complication of ischemic stroke. The mechanism of the blood-brain barrier opening that underlies the edema formation is poorly understood. In the present study we examined the response of endothelial cells cultured from adult human brain to thrombogenic and fibrinolytic factors that possibly accumulate in the occluded vascular segments in ischemic stroke. METHODS The changes in the morphology of cultured human brain microvascular… CONTINUE READING

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