Contraction-mediated pinocytosis of RGD-peptide by dermal fibroblasts: inhibition of matrix attachment blocks contraction and disrupts microfilament organisation.

Abstract

Force generation in collagen and matrix contraction are basic functions of fibroblasts and important elements of tissue repair. Cell-matrix attachment is critical to this contraction, involving RGD-binding integrins. We have investigated how this process operates, in terms of force generation (in the Culture Force Monitor) and cytoskeletal structure, using… (More)

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Cite this paper

@article{Sethi2002ContractionmediatedPO, title={Contraction-mediated pinocytosis of RGD-peptide by dermal fibroblasts: inhibition of matrix attachment blocks contraction and disrupts microfilament organisation.}, author={Khushbu Sethi and Vivek C Mudera and R Sutterlin and Werner Baschong and R. A. Brown}, journal={Cell motility and the cytoskeleton}, year={2002}, volume={52 4}, pages={231-41} }