Contraction-activated glucose uptake is normal in insulin-resistant muscle of the obese Zucker rat.

@article{Brozinick1992ContractionactivatedGU,
  title={Contraction-activated glucose uptake is normal in insulin-resistant muscle of the obese Zucker rat.},
  author={Joseph T. Brozinick and Garrett J Etgen and Ben B. Yaspelkis and John L. Ivy},
  journal={Journal of applied physiology},
  year={1992},
  volume={73 1},
  pages={382-7}
}
The rates of muscle glucose uptake of lean and obese Zucker rats were assessed via hindlimb perfusion under basal conditions (no insulin), in the presence of a maximal insulin concentration (10 mU/ml), and after electrically stimulated muscle contraction in the absence of insulin. The perfusate contained 28 mM glucose and 7.5 microCi/mmol of 2-deoxy-D-[3H-(G)]glucose. Glucose uptake rates in the soleus (slow-twitch oxidative fibers), red gastrocnemius (fast-twitch oxidative-glycolytic fibers… CONTINUE READING