Contractile protein function in failing and nonfailing human myocardium.

@article{Hasenfuss1992ContractilePF,
  title={Contractile protein function in failing and nonfailing human myocardium.},
  author={Gerd Hasenfuss and Louis A. Mulieri and Bruce J. Leavitt and Paul D. Allen and C H Holubarsch and Hanjorg Just and Norman R. Alpert},
  journal={Basic research in cardiology},
  year={1992},
  volume={87 Suppl 1},
  pages={107-16}
}
Isometric heat and force measurements were used to relate mechanical performance to function of contractile proteins in muscle strips from failing and nonfailing human hearts (37 degrees C, 60 beats per minute). Compared to control myocardium, crossbridge behavior was altered in myocardium from hearts with end-stage failing dilated and ischemic… CONTINUE READING