Contractile properties of the pig bladder mucosa in response to neurokinin A: a role for myofibroblasts?

@article{Sadananda2008ContractilePO,
  title={Contractile properties of the pig bladder mucosa in response to neurokinin A: a role for myofibroblasts?},
  author={Prajni Sadananda and R Chess-Williams and Elizabeth Burcher},
  journal={British journal of pharmacology},
  year={2008},
  volume={153 7},
  pages={
          1465-73
        }
}
BACKGROUND AND PURPOSE The bladder urothelium is now known to have active properties. Our aim was to investigate the contractile properties of the urinary mucosa in response to the tachykinin neurokinin A (NKA) and carbachol. EXPERIMENTAL APPROACH Discrete concentration-response curves for carbachol and NKA were obtained in matched strips of porcine detrusor, mucosa and intact bladder, suspended in organ baths. The effects of inhibitors and tachykinin receptor antagonists were studied on NKA… CONTINUE READING

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