Contractile filament architecture and force transmission in swine airway smooth muscle.

@article{Kuo2004ContractileFA,
  title={Contractile filament architecture and force transmission in swine airway smooth muscle.},
  author={Kuo-Hsing Kuo and Chun Y Seow},
  journal={Journal of cell science},
  year={2004},
  volume={117 Pt 8},
  pages={1503-11}
}
It is well known that the cyclic interaction of myosin cross bridges with actin filaments is responsible for force and shortening generation in smooth muscle. The intracellular organization of contractile filaments, however, is still poorly understood. Here, we show electron microscopic and functional evidence that contractile filaments in airway smooth muscle lie parallel to the longitudinal axis of the cell bundle, in contrast to the obliquely arranged filaments depicted in conventional… CONTINUE READING
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Organization of contractile / cytoskeletal elements

  • R. M. Bagby
  • Biochemistry of Smooth Muscle
  • 1983
Highly Influential
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