Contractile and metabolic properties of engineered skeletal muscle derived from slow and fast phenotype mouse muscle.

@article{Khodabukus2015ContractileAM,
  title={Contractile and metabolic properties of engineered skeletal muscle derived from slow and fast phenotype mouse muscle.},
  author={Alastair Khodabukus and Keith Baar},
  journal={Journal of cellular physiology},
  year={2015},
  volume={230 8},
  pages={1750-7}
}
Satellite cells derived from fast and slow muscles have been shown to adopt contractile and metabolic properties of their parent muscle. Mouse muscle shows less distinctive fiber-type profiles than rat or rabbit muscle. Therefore, in this study we sought to determine whether three-dimensional muscle constructs engineered from slow soleus (SOL) and fast tibialis anterior (TA) from mice would adopt the contractile and metabolic properties of their parent muscle. Time-to-peak tension (TPT) and… CONTINUE READING
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