Contraceptive and Therapeutic Effects of the Levonorgestrel Intrauterine System: An Overview

  title={Contraceptive and Therapeutic Effects of the Levonorgestrel Intrauterine System: An Overview},
  author={J. Jensen},
  journal={Obstetrical & Gynecological Survey},
  • J. Jensen
  • Published 2005
  • Medicine
  • Obstetrical & Gynecological Survey
  • The levonorgestrel intrauterine system (LNG IUS), a steroid-releasing intrauterine system, is a T-shaped device that releases levonorgestrel directly into the uterine cavity at an initial rate of 20 &mgr;g per day. The contraceptive and therapeutic benefits of the LNG IUS stem primarily from its local effects. The local hormone delivery causes high levonorgestrel levels in the endometrial tissue but low levels in the systemic circulation. This leads to strong endometrial suppression and, in… CONTINUE READING
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