Continuous time-domain analysis of cerebrovascular autoregulation using near-infrared spectroscopy.

@article{Brady2007ContinuousTA,
  title={Continuous time-domain analysis of cerebrovascular autoregulation using near-infrared spectroscopy.},
  author={Ken M. Brady and Jennifer K Lee and Kathleen Kazuko Kibler and Piotr Smielewski and Marek Czosnyka and Ronald Blaine Easley and Raymond C Koehler and Donald H. Shaffner},
  journal={Stroke},
  year={2007},
  volume={38 10},
  pages={
          2818-25
        }
}
BACKGROUND AND PURPOSE Assessment of autoregulation in the time domain is a promising monitoring method for actively optimizating cerebral perfusion pressure (CPP) in critically ill patients. The ability to detect loss of autoregulatory vasoreactivity to spontaneous fluctuations in CPP was tested with a new time-domain method that used near-infrared spectroscopic measurements of tissue oxyhemoglobin saturation in an infant animal model. METHODS Piglets were made progressively hypotensive over… CONTINUE READING

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