Continuous subcutaneous insulin infusion--an historical perspective.

  title={Continuous subcutaneous insulin infusion--an historical perspective.},
  author={Jay S Skyler},
  journal={Diabetes technology & therapeutics},
  volume={12 Suppl 1},
Insulin became available for the treatment of diabetes mellitus in the early 1920s. From that time onward, as noted by Robert Tattersall in his historical review ‘‘The Quest for Normoglycemia,’’ there has been an ongoing struggle by diabetologists and their patients to maintain glycemic control as close to normal as possible. For many years, it was uncertain what constituted normal insulin physiology. Our understanding of that really commenced after the development of the insulin… CONTINUE READING