Continuous subcutaneous infusions of growth hormone (GH) releasing hormone 1-44 for 14 days increase GH and insulin-like growth factor-I levels in old men.

@article{Corpas1993ContinuousSI,
  title={Continuous subcutaneous infusions of growth hormone (GH) releasing hormone 1-44 for 14 days increase GH and insulin-like growth factor-I levels in old men.},
  author={E. Corpas and S. Mitchell Harman and M A Pi{\~n}eyro and Race Roberson and Marc R. Blackman},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1993},
  volume={76 1},
  pages={
          134-8
        }
}
Twice daily sc injections of GHRH increase serum GH and IGF-I levels in healthy old men to values like those of untreated young men by producing high amplitude GH peaks after the injections. In the present study, we measured baseline insulin-like growth factor-I (IGF-I) 24-h profiles of GH release, and responses to GHRH stimulation tests in healthy young and old men. Old men were then given, in random order, 1 and 2 mg continuous sc GHRH 1-44 infusions daily for 14 days with an intervening 14… CONTINUE READING

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Endocrine Aspects of Successful Aging: Genes, Hormones and Lifestyles

  • Research and Perspectives in Endocrine Interactions
  • 2004
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