Continuous particle separation in spiral microchannels using Dean flows and differential migration.

@article{Bhagat2008ContinuousPS,
  title={Continuous particle separation in spiral microchannels using Dean flows and differential migration.},
  author={Ali Asgar S. Bhagat and Sathyakumar S. Kuntaegowdanahalli and Ian Papautsky},
  journal={Lab on a chip},
  year={2008},
  volume={8 11},
  pages={1906-14}
}
Microparticle separation and concentration based on size has become indispensable in many biomedical and environmental applications. In this paper we describe a passive microfluidic device with spiral microchannel geometry for complete separation of particles. The design takes advantage of the inertial lift and viscous drag forces acting on particles of various sizes to achieve differential migration, and hence separation, of microparticles. The dominant inertial forces and the Dean rotation… CONTINUE READING
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