Continuous models fail to capture details of reentry in fibrotic myocardium

Cardiac arrhythmias have traditionally been simulated using continuous models that assume tissue homogeneity and use a relatively large spatial discretization. However, it is believed the tissue fibrosis and collagen deposition, which occur on a micron-level scale, are critical factors in arrhythmogenesis, and it remains unclear how well continuous models… CONTINUE READING