Continuous lymphoid cell lines with characteristics of B cells (bone-marrow-derived), lacking the Epstein-Barr virus genome and derived from three human lymphomas.

@article{Klein1974ContinuousLC,
  title={Continuous lymphoid cell lines with characteristics of B cells (bone-marrow-derived), lacking the Epstein-Barr virus genome and derived from three human lymphomas.},
  author={Georg Klein and T. Lindahl and Mikael Jondal and Wolfgang Leibold and Jose Roberto de Menezes and Kenneth Nilsson and Christer Sundstr{\"o}m},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1974},
  volume={71 8},
  pages={3283-6}
}
Three exceptional cell lines have been tested for the presence of the Epstein-Barr virus genome by nucleic acid hybridization (complementary RNA.DNA) and Epstein-Barr virus-determined nuclear antigen tests. Two lines were derived from Swedish lymphoma cases and one from an African Burkitt-like lymphoma biopsy that was negative for Epstein-Barr virus DNA and the virus-determined nuclear antigen. All three lines apparently lacked the viral genome. Two of the three lines clearly had… CONTINUE READING

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