Continuous local intra-arterial nimodipine administration in severe symptomatic vasospasm after subarachnoid hemorrhage.

@article{Musahl2011ContinuousLI,
  title={Continuous local intra-arterial nimodipine administration in severe symptomatic vasospasm after subarachnoid hemorrhage.},
  author={Christian Musahl and H Henkes and Zsolt Vajda and Jan Coburger and Nikolai J. Hopf},
  journal={Neurosurgery},
  year={2011},
  volume={68 6},
  pages={1541-7; discussion 1547}
}
BACKGROUND Cerebral vasospasm (CV) is a potentially disastrous consequence of subarachnoid hemorrhage despite medical treatment. Nimodipine is a potent drug for vessel relaxation, but side effects may preclude a sufficient dose. OBJECTIVE To explore whether continuous local intra-arterial nimodipine administration (CLINA) can reverse vasospasm and prevent delayed ischemic neurological deficit. METHODS Six consecutive subarachnoid hemorrhage patients (5 women; mean age, 47.2 years) with… CONTINUE READING