Continuous intrapulmonary distension with perfluorocarbon accelerates neonatal (but not adult) lung growth.

@article{Nobuhara1998ContinuousID,
  title={Continuous intrapulmonary distension with perfluorocarbon accelerates neonatal (but not adult) lung growth.},
  author={Kerilyn K. Nobuhara and Dario O. Fauza and John W Difiore and Michael H. Hines and James C. Fackler and Robert Slavin and R. Hirschl and J Michael Wilson},
  journal={Journal of pediatric surgery},
  year={1998},
  volume={33 2},
  pages={292-8}
}
BACKGROUND/PURPOSE We have previously demonstrated that experimental fetal tracheal ligation reverses the structural and physiological effects of pulmonary hypoplasia associated with congenital diaphragmatic hernia. The purpose of this study was to determine if lung growth could be similarly accelerated postnatally by continuous liquid-based intrapulmonary distension. METHODS Ten neonatal lambs were divided into two experimental groups. Five neonatal animals underwent a right thoracotomy with… CONTINUE READING