Continuous increase of epileptogenic effects following application of proteolytic enzymes (buccal ganglia of Helix pomatia).

@article{Altrup2004ContinuousIO,
  title={Continuous increase of epileptogenic effects following application of proteolytic enzymes (buccal ganglia of Helix pomatia).},
  author={Ulrich Altrup and Atik Ure and A Joschko},
  journal={Acta biologica Hungarica},
  year={2004},
  volume={55 1-4},
  pages={269-72}
}
Epileptic activity of neurons consists of paroxysmal depolarization shifts (PDS) which can be induced presumably in any nervous system by application of an epileptogenic drug. The spontaneous appearance of epileptic activity, however, is based on a largely unknown process which increases susceptibility to epileptic activity (seizure susceptibility in man). It is presently shown that the treatment of ganglia with proteolytic enzymes (Pronase) decreases the effective concentration of… CONTINUE READING