Continuous high-frequency stimulation in freely moving rats: development of an implantable microstimulation system.

@article{Harnack2008ContinuousHS,
  title={Continuous high-frequency stimulation in freely moving rats: development of an implantable microstimulation system.},
  author={Daniel Harnack and Wassilios Meissner and Raik Paulat and Hannes Hilgenfeld and W. Mueller and Christine Winter and Rudolf Morgenstern and Andreas Kupsch},
  journal={Journal of neuroscience methods},
  year={2008},
  volume={167 2},
  pages={278-91}
}
High-frequency stimulation (HFS) of basal ganglia and thalamic nuclei is an established treatment for various movement disorders and has recently been extended to other neuro-psychiatric conditions. Numerous experimental studies in small laboratory animals provided important insights in the mode of action of HFS. However, the interpretation of the results is often limited by the use of short-term HFS, while patients receive continuous stimulation for many years. One reason is the lack of an… CONTINUE READING