Continuous epidermal growth factor delivery in corneal epithelial wound healing.

  title={Continuous epidermal growth factor delivery in corneal epithelial wound healing.},
  author={Heather Sheardown and Claire Wedge and L H Chou and Robert Apel and David S. Rootman and Yan-wah Cheng},
  journal={Investigative ophthalmology & visual science},
  volume={34 13},
PURPOSE To investigate the effects of a single prolonged exposure to recombinant epidermal growth factor on the healing of anterior keratotomy wounds in New Zealand white rabbits. METHODS After wounding, eyes were perfused for 1, 2, 4, and 8 hours with either epidermal growth factor solution at a concentration of 50 micrograms/ml or balanced saline solution using a Morgan therapeutic lens (Mortan Inc, Missoula MT) and a syringe pump. Furthermore, concentration response was evaluated by… CONTINUE READING

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