Continuous contractile activity induces fiber type specific expression of HSP70 in skeletal muscle.

@article{Neufer1996ContinuousCA,
  title={Continuous contractile activity induces fiber type specific expression of HSP70 in skeletal muscle.},
  author={P. Darrell Neufer and George A. Ordway and Gregory Allen Hand and John M Shelton and J. A. Richardson and Ivor J. Benjamin and R. Sanders Williams},
  journal={The American journal of physiology},
  year={1996},
  volume={271 6 Pt 1},
  pages={C1828-37}
}
Continuous contractile activity of skeletal muscle elicits an early and dramatic increase in ribosomal RNA, suggesting that translational efficiency and/or capacity is enhanced during the adaptive response to increased metabolic demand. In view of the important role heat shock or stress proteins (HSPs) play as molecular chaperones during protein synthesis, we examined whether expression of the inducible 70-kDa HSP (HSP70) and/or mitochondrial 60-kDa HSP (HSP60) is altered in rabbit tibialis… CONTINUE READING

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