Continuous aortic flow augmentation: a pilot study of hemodynamic and renal responses to a novel percutaneous intervention in decompensated heart failure.

@article{Konstam2005ContinuousAF,
  title={Continuous aortic flow augmentation: a pilot study of hemodynamic and renal responses to a novel percutaneous intervention in decompensated heart failure.},
  author={Marvin A. Konstam and Barbara Czerska and Michael B{\"o}hm and Ron M. Oren and Jerzy Sadowski and Sanjaya Khanal and William T. Abraham and Andrae Wasler and J. Dahm and Antonello Gavazzi and Sinisa Dj Gradinac and Victor L Legrand and Paul Mohacsi and Gerhard Poelzl and Branislav Radovancevi{\'c} and Adrian B. Van Bakel and Michael R. Zile and Barry M Cabuay and Krzysztof Bartuś and Piet Jansen},
  journal={Circulation},
  year={2005},
  volume={112 20},
  pages={3107-14}
}
BACKGROUND Diminished aortic flow may induce adverse downstream vascular and renal signals. Investigations in a heart failure animal model have shown that continuous aortic flow augmentation (CAFA) achieves hemodynamic improvement and ventricular unloading, which suggests a novel therapeutic approach to patients with heart failure exacerbation that is inadequately responsive to medical therapy. METHODS AND RESULTS We studied 24 patients (12 in Europe and 12 in the United States) with heart… CONTINUE READING