Continuous Noninvasive Orthostatic Blood Pressure Measurements and Their Relationship with Orthostatic Intolerance, Falls, and Frailty in Older People

  title={Continuous Noninvasive Orthostatic Blood Pressure Measurements and Their Relationship with Orthostatic Intolerance, Falls, and Frailty in Older People},
  author={Rom{\'a}n Romero-Ortu{\~n}o and Lisa Cogan and Timothy G. Foran and Rose Anne Kenny and Chie Wei Fan},
  journal={Journal of the American Geriatrics Society},
OBJECTIVES: To identify morphological orthostatic blood pressure (BP) phenotypes in older people and assess their correlation with orthostatic intolerance (OI), falls, and frailty and to compare the discriminatory performance of a morphological classification with two established orthostatic hypotension (OH) definitions: consensus (COH) and initial (IOH). 

Impaired Orthostatic Blood Pressure Recovery Is Associated with Unexplained and Injurious Falls

To determine for the first time to what extent OH (and variants) are risk factors for incident falls, unexplained falls (UF), injurious falls (IF) and syncope using dynamic blood pressure (BP) measurements in a population study.

Orthostatic Hypotension in Older Adults

This study used a continuous noninvasive blood pressure monitoring device to measure orthostatic change on a single occasion in 442 community-dwelling, older adults from Ireland to measure baseline supine systolic blood pressure.

Sub‐clinical orthostatic hypotension is associated with greater subjective memory impairment in older adults

This work hypothesised that sub‐clinical orthostatic hypotension would be associated with SMI and explored these associations according to sex.

Orthostatic Hypotension in the Elderly: A Marker of Clinical Frailty?

Orthostatic blood pressure recovery associates with physical performance, frailty and number of falls in geriatric outpatients

DBP recovery was particularly associated with clinical outcome in geriatric outpatients, suggesting BP recovery to be of clinical interest.

Orthostatic hypotension (OH) and mortality in relation to age, blood pressure and frailty.

Association of Orthostatic Hypotension Timing With Clinical Events in Adults With Diabetes and Hypertension: Results From the ACCORD Trial.

Findings support the use of a flexibly timed, single measurement to assess OH in clinical practice and suggest BP treatment goal did not increase risk of OH regardless of timing, and neither single time nor set of measurements were clearly superior with regard to outcomes.

Orthostatic reactions and cognitive dysfunctions in elderly and senile patients with arterial hypertension

A decrease in cognitive functions was observed in patients with COH compared with patients without OHR, and OHR was detected in 31% of patients with arterial hypertension in older age groups.

Diminished Dynamic Physical Performance Is Associated With Orthostatic Hypotension in Geriatric Outpatients

Dynamic physical performance tests with a substantial postural change and center of mass displacement were significantly associated with OH, and the influence of physical performance in daily routine activities should be further explored to establish counteracting interventions.



Orthostatic Hypotension and Risk of Cardiovascular Disease in Elderly People: The Rotterdam Study

To determine the prognostic role of orthostatic hypotension for cardiovascular disease (CVD) and all‐cause mortality in elderly people, a large number of elderly people with a history of CVD are surveyed.

Intolerance to initial orthostasis relates to systolic BP changes in elders

This study suggests that orthostatic SBP changes may be more important than DBP changes as determinants of early OI during active stand and the crucial importance of the quick recovery of SBP in order to avoid OI is biologically plausible.

Measuring orthostatic hypotension with the Finometer device: is a blood pressure drop of one heartbeat clinically relevant?

Orthostatic hypotension and falls are correlated when using Finometry, with the best association found when using 5-s averages, irrespective of the method or time average that is applied.

Prevalence of orthostatic hypotension

  • P. Low
  • Medicine
    Clinical Autonomic Research
  • 2007
The prevalence of OH increases with age, with disorders that affect autonomic nerve transmission, and with increasingly severe orthostatic stress, including diabetic neuropathy and Parkinson’s disease.

The association between orthostatic hypotension and medication use in the British Women's Heart and Health Study.

OBJECTIVE to determine the prevalence of orthostatic hypotension (OH) and associations with medication use in community-dwelling older women. DESIGN cross-sectional analysis using data from the

The consensus statement on the definition of orthostatic hypotension: a revisit after 13 years.

Orthostatic hypotension is a physical sign that reflects a final common pathway of various forms of disordered physiology. As such, it stimulates particular interest among clinical physiologists,

Postural Blood Pressure Changes and Orthostatic Hypotension in the Elderly Patient

A detailed patient history, an accurate orthostatic blood pressure measurement and careful evaluation of the autonomic nervous system can provide clinical guidance for management of OH and the use of antihypertensive medication can be safe and lead to a low risk of developing OH.

Orthostatic hypotension predicts mortality in elderly men: the Honolulu Heart Program.

Orthostatic hypotension is relatively uncommon, may be a marker for physical frailty, and is a significant independent predictor of 4-year all-cause mortality in this cohort of elderly ambulatory men.

Orthostatic Hypotension Predicts Mortality in Middle-Aged Adults: The Atherosclerosis Risk in Communities (ARIC) Study

OH predicts mortality in middle-aged adults and is only partly explained by traditional risk factors for cardiovascular disease and overall mortality.

Postural changes in blood pressure and the prevalence of orthostatic hypotension among home-dwelling elderly aged 75 years or older

OH and postural changes in BP are more common among the home-dwelling elderly than reported in previous studies and the prevalence of OH is related to the number of medicines in regular use.