Continuing Evolution of Burkholderia mallei Through Genome Reduction and Large-Scale Rearrangements

@inproceedings{Losada2010ContinuingEO,
  title={Continuing Evolution of Burkholderia mallei Through
                    Genome Reduction and Large-Scale Rearrangements},
  author={Liliana Losada and Catherine M. Ronning and David DeShazer and Donald E. Woods and Natalie D. Fedorova and H. Stanley Kim and Svetlana A. Shabalina and Talima Pearson and Lauren M. Brinkac and Patrick O. B. Tan and Tannistha Nandi and Jonathan Crabtree and Jonathan H. Badger and Steve Beckstrom-Sternberg and Muhammad Najmus Saqib and Steven E. Schutzer and Paul S Keim and William C. Nierman},
  booktitle={Genome biology and evolution},
  year={2010}
}
Burkholderia mallei (Bm), the causative agent of the predominately equine disease glanders, is a genetically uniform species that is very closely related to the much more diverse species Burkholderia pseudomallei (Bp), an opportunistic human pathogen and the primary cause of melioidosis. To gain insight into the relative lack of genetic diversity within Bm, we performed whole-genome comparative analysis of seven Bm strains and contrasted these with eight Bp strains. The Bm core genome (shared… CONTINUE READING
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