Continuation of metformin reduces early pregnancy loss in obese Pakistani women with polycystic ovarian syndrome.

@article{Nawaz2010ContinuationOM,
  title={Continuation of metformin reduces early pregnancy loss in obese Pakistani women with polycystic ovarian syndrome.},
  author={Fauzia Haq Nawaz and Javed Haider Rizvi},
  journal={Gynecologic and obstetric investigation},
  year={2010},
  volume={69 3},
  pages={184-9}
}
BACKGROUND Polycystic ovarian syndrome (PCOS) is the most common cause of anovulatory infertility worldwide. In addition to a poor conception rate, pregnancy loss rates are significantly higher (30-50%) during the first trimester in women with PCOS. Insulin resistance (IR) in this syndrome is not only implicated toward early pregnancy loss (EPL) but also pathognomic for various obstetrical complications during pregnancy. We evaluated the role of Metformin in the reduction of EPL in women with… CONTINUE READING
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