Continuation of metformin in the first trimester of women with polycystic ovarian syndrome is not associated with increased perinatal morbidity

@article{Bolton2008ContinuationOM,
  title={Continuation of metformin in the first trimester of women with polycystic ovarian syndrome is not associated with increased perinatal morbidity},
  author={Susan Cross Bolton and Barbara B Cleary and John William Tudor Walsh and Eugene P Dempsey and Michael J. Turner},
  journal={European Journal of Pediatrics},
  year={2008},
  volume={168},
  pages={203-206}
}
This study aimed to assess the perinatal outcome, especially foetal growth, following the continuation of metformin during the first trimester of pregnancy. All women with polycystic ovary syndrome (PCOS) treated with metformin in the first trimester and who delivered a baby weighing 500 g or more between 2003 and 2005 were studied. Subjects were matched for age and parity with randomly selected controls. The perinatal outcomes studied were: growth parameters, gestational age, congenital… CONTINUE READING
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