Continuation electroconvulsive therapy vs pharmacotherapy for relapse prevention in major depression: a multisite study from the Consortium for Research in Electroconvulsive Therapy (CORE).

@article{Kellner2006ContinuationET,
  title={Continuation electroconvulsive therapy vs pharmacotherapy for relapse prevention in major depression: a multisite study from the Consortium for Research in Electroconvulsive Therapy (CORE).},
  author={C. Kellner and R. Knapp and G. Petrides and T. Rummans and M. Husain and K. Rasmussen and M. Mueller and H. Bernstein and Kevin O'Connor and G. Smith and M. Biggs and S. Bailine and C. Malur and E. Yim and S. McClintock and S. Sampson and M. Fink},
  journal={Archives of general psychiatry},
  year={2006},
  volume={63 12},
  pages={
          1337-44
        }
}
  • C. Kellner, R. Knapp, +14 authors M. Fink
  • Published 2006
  • Psychology, Medicine
  • Archives of general psychiatry
  • BACKGROUND Although electroconvulsive therapy (ECT) has been shown to be extremely effective for the acute treatment of major depression, it has never been systematically assessed as a strategy for relapse prevention. OBJECTIVE To evaluate the comparative efficacy of continuation ECT (C-ECT) and the combination of lithium carbonate plus nortriptyline hydrochloride (C-Pharm) in the prevention of depressive relapse. DESIGN Multisite, randomized, parallel design, 6-month trial performed from… CONTINUE READING
    364 Citations

    Paper Mentions

    Interventional Clinical Trial
    The study aims to compare outcomes of Electroconvulsive Therapy (ECT) using ketamine versus methohexital anesthesia in depressed patients. The investigators hypothesize that patients… Expand
    ConditionsBipolar Depression, Unipolar Depression
    InterventionDrug
    Interventional Clinical Trial
    This study will determine whether medications alone or medications and electroconvulsive therapy (ECT) work best to prevent depressive relapse and to improve quality of life for… Expand
    ConditionsDepression
    InterventionDrug, Procedure
    Interventional Clinical Trial
    The purpose of the study is to determine if continuation electroconvulsive therapy (ECT) is safe and effective in relapse prevention of depression.  
    ConditionsDepressive Disorder, Major
    InterventionDrug, Procedure
    Combination of Pharmacotherapy With Electroconvulsive Therapy in Prevention of Depressive Relapse: A Pilot Controlled Trial
    • 16
    • Highly Influenced

    References

    SHOWING 1-10 OF 28 REFERENCES
    Continuation pharmacotherapy in the prevention of relapse following electroconvulsive therapy: a randomized controlled trial.
    • 562
    • Highly Influential
    • PDF
    Effectiveness of electroconvulsive therapy in community settings
    • 199
    • PDF
    ECT Remission Rates in Psychotic Versus Nonpsychotic Depressed Patients: A Report from CORE
    • 364
    One-year follow-up after successful ECT: a naturalistic study in depressed inpatients.
    • 29
    The influence of age on the response of major depression to electroconvulsive therapy: a C.O.R.E. Report.
    • M. O’Connor, R. Knapp, +9 authors C. Kellner
    • Psychology, Medicine
    • The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
    • 2001
    • 203
    Continuation treatment of delusional depression in older adults.
    • B. Meyers, S. Klimstra, +4 authors G. Alexopoulos
    • Psychology, Medicine
    • The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
    • 2001
    • 39
    Relief of expressed suicidal intent by ECT: a consortium for research in ECT study.
    • 182
    Tachyphylaxis in unipolar major depressive disorder.
    • 51