Continuation electroconvulsive therapy vs pharmacotherapy for relapse prevention in major depression: a multisite study from the Consortium for Research in Electroconvulsive Therapy (CORE).
@article{Kellner2006ContinuationET, title={Continuation electroconvulsive therapy vs pharmacotherapy for relapse prevention in major depression: a multisite study from the Consortium for Research in Electroconvulsive Therapy (CORE).}, author={C. Kellner and R. Knapp and G. Petrides and T. Rummans and M. Husain and K. Rasmussen and M. Mueller and H. Bernstein and Kevin O'Connor and G. Smith and M. Biggs and S. Bailine and C. Malur and E. Yim and S. McClintock and S. Sampson and M. Fink}, journal={Archives of general psychiatry}, year={2006}, volume={63 12}, pages={ 1337-44 } }
BACKGROUND
Although electroconvulsive therapy (ECT) has been shown to be extremely effective for the acute treatment of major depression, it has never been systematically assessed as a strategy for relapse prevention.
OBJECTIVE
To evaluate the comparative efficacy of continuation ECT (C-ECT) and the combination of lithium carbonate plus nortriptyline hydrochloride (C-Pharm) in the prevention of depressive relapse.
DESIGN
Multisite, randomized, parallel design, 6-month trial performed from… CONTINUE READING
Paper Mentions
Interventional Clinical Trial
The study aims to compare outcomes of Electroconvulsive Therapy (ECT) using ketamine versus
methohexital anesthesia in depressed patients. The investigators hypothesize that patients… Expand
Conditions | Bipolar Depression, Unipolar Depression |
---|---|
Intervention | Drug |
Interventional Clinical Trial
This study will determine whether medications alone or medications and electroconvulsive
therapy (ECT) work best to prevent depressive relapse and to improve quality of life for… Expand
Conditions | Depression |
---|---|
Intervention | Drug, Procedure |
Interventional Clinical Trial
The purpose of the study is to determine if continuation electroconvulsive therapy (ECT) is
safe and effective in relapse prevention of depression.
Conditions | Depressive Disorder, Major |
---|---|
Intervention | Drug, Procedure |
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