Continuation electroconvulsive therapy vs pharmacotherapy for relapse prevention in major depression: a multisite study from the Consortium for Research in Electroconvulsive Therapy (CORE).

@article{Kellner2006ContinuationET,
  title={Continuation electroconvulsive therapy vs pharmacotherapy for relapse prevention in major depression: a multisite study from the Consortium for Research in Electroconvulsive Therapy (CORE).},
  author={Charles H Kellner and Rebecca G. Knapp and Georgios Petrides and Teresa A. Rummans and Mustafa M. Husain and Keith G. Rasmussen and Martina Mueller and Hilary J. Bernstein and Kevin O'Connor and Glenn E. Smith and Melanie M. Biggs and Samuel H. Bailine and Chitra Malur and Eunsil Yim and Shawn M. McClintock and Shirlene M. Sampson and M Fink},
  journal={Archives of general psychiatry},
  year={2006},
  volume={63 12},
  pages={
          1337-44
        }
}
BACKGROUND Although electroconvulsive therapy (ECT) has been shown to be extremely effective for the acute treatment of major depression, it has never been systematically assessed as a strategy for relapse prevention. OBJECTIVE To evaluate the comparative efficacy of continuation ECT (C-ECT) and the combination of lithium carbonate plus nortriptyline hydrochloride (C-Pharm) in the prevention of depressive relapse. DESIGN Multisite, randomized, parallel design, 6-month trial performed from… CONTINUE READING

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