Context shapes: Efficient complementary shape matching for protein-protein docking.

@article{Shentu2008ContextSE,
  title={Context shapes: Efficient complementary shape matching for protein-protein docking.},
  author={Zujun Shentu and Mohammad Al Hasan and Christopher Bystroff and Mohammed J. Zaki},
  journal={Proteins},
  year={2008},
  volume={70 3},
  pages={1056-73}
}
We describe an efficient method for partial complementary shape matching for use in rigid protein-protein docking. The local shape features of a protein are represented using boolean data structures called Context Shapes. The relative orientations of the receptor and ligand surfaces are searched using precalculated lookup tables. Energetic quantities are derived from shape complementarity and buried surface area computations, using efficient boolean operations. Preliminary results indicate that… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 33 references

Similar Papers

Loading similar papers…