Context-dependent modulation of hippocampal and cortical recruitment during remote spatial memory retrieval.

@article{Lopez2012ContextdependentMO,
  title={Context-dependent modulation of hippocampal and cortical recruitment during remote spatial memory retrieval.},
  author={Jo{\"e}lle Lopez and Karin Herbeaux and Brigitte Cosquer and Michel Engeln and Christophe Muller and Christine Lazarus and Christian Kelche and Bruno Bontempi and J F Cassel and Anne Pereira de Vasconcelos},
  journal={Hippocampus},
  year={2012},
  volume={22 4},
  pages={827-41}
}
According to systems consolidation, as hippocampal-dependent memories mature over time, they become additionally (or exclusively) dependent on extra-hippocampal structures. We assessed the recruitment of hippocampal and cortical structures on remote memory retrieval in a performance-degradation resistant (PDR; no performance degradation with time) versus performance-degradation prone (PDP; performance degraded with time) context. Using a water-maze task in two contexts with a hidden platform… CONTINUE READING
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