Contemporary management of locally advanced rectal cancer: Resolving issues, controversies and shifting paradigms.

Abstract

Advancements in rectal cancer treatment have resulted in improvement only in locoregional control and have failed to address distant relapse, which is the predominant mode of treatment failure in rectal cancer. As the efficacy of conventional chemoradiotherapy (CRT) followed by total mesorectal excision (TME) reaches a plateau, the need for alternative… (More)
DOI: 10.21147/j.issn.1000-9604.2018.01.14

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