Contemporary activity of colistin and polymyxin B against a worldwide collection of Gram-negative pathogens: results from the SENTRY Antimicrobial Surveillance Program (2006-09).

@article{Gales2011ContemporaryAO,
  title={Contemporary activity of colistin and polymyxin B against a worldwide collection of Gram-negative pathogens: results from the SENTRY Antimicrobial Surveillance Program (2006-09).},
  author={Ana Cristina Gales and Ronald N. Jones and H{\'e}lio S. Sader},
  journal={The Journal of antimicrobial chemotherapy},
  year={2011},
  volume={66 9},
  pages={2070-4}
}
OBJECTIVES To comparatively evaluate the antimicrobial activities of colistin and polymyxin B with those of other antimicrobials against a worldwide collection of 40 625 Gram-negative bacilli. METHODS Antimicrobial susceptibility testing was performed and interpreted using the CLSI broth microdilution method except for colistin against Enterobacteriaceae. RESULTS The polymyxins showed potent in vitro activities (MIC₉₀, ≤ 0.5-1 mg/L) against this large collection of clinical isolates, with… CONTINUE READING
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