Contemporary Diagnosis and Management of Patients With Myocardial Infarction in the Absence of Obstructive Coronary Artery Disease: A Scientific Statement From the American Heart Association

@article{TamisHolland2019ContemporaryDA,
  title={Contemporary Diagnosis and Management of Patients With Myocardial Infarction in the Absence of Obstructive Coronary Artery Disease: A Scientific Statement From the American Heart Association},
  author={J. Tamis-Holland and H. Jneid and H. Reynolds and S. Agewall and E. Brilakis and T. Brown and A. Lerman and M. Cushman and D. Kumbhani and C. Arslanian-Engoren and A. Bolger and J. Beltrame},
  journal={Circulation},
  year={2019},
  volume={139},
  pages={e891–e908}
}
Myocardial infarction in the absence of obstructive coronary artery disease is found in ≈5% to 6% of all patients with acute infarction who are referred for coronary angiography. There are a variety of causes that can result in this clinical condition. As such, it is important that patients are appropriately diagnosed and an evaluation to uncover the correct cause is performed so that, when possible, specific therapies to treat the underlying cause can be prescribed. This statement provides a… Expand

Paper Mentions

Observational Patient Registry Clinical Trial
Myocardial infarction with non-obstructive coronary arteries (MINOCA) occurs in 1-13% of all patients with acute myocardial infarction (AMI). According to most studies MINOCA patients… Expand
ConditionsMyocardial Infarction With Nonobstructive Coronary Arteries
InterventionDiagnostic Test
Observational Patient Registry Clinical Trial
The MINOCA-GR registry will be the first nationwide study aiming to obtain data regarding prevalence, demographics, clinical profile, previous anginal status, presence of… Expand
ConditionsAcute Myocardial Infarction, Angina Pectoris, Coronary Microvascular Disease, (+2 more)
InterventionDiagnostic Test, Other
Guidelines for the management of myocardial infarction/injury with non-obstructive coronary arteries (MINOCA): a position paper from the Dutch ACS working group
TLDR
This position paper of the Dutch ACS working group of the Netherlands Society of Cardiology aims to stress the importance of considering MINOCA as a dynamic working diagnosis and to guide the clinician in the management of patients withMINOCA by proposing a clinical diagnostic algorithm. Expand
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TLDR
The authors review the contemporary definition, etiologies and assessment, and management for AMI patients with MINOCA. Expand
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TLDR
Determining the cause of MINOCA and excluding other possible causes for cardiac troponin elevation has notable implications for tailoring secondary prevention measures aimed at improving the overall prognosis of AMI. Expand
Myocardial Infarction with Non-Obstructive Coronary Arteries: Contemporary Diagnostic and Management Approaches
TLDR
A review of the etiology and pathogenesis of MINOCA, diagnostic work-up methods and individualized treatment approaches reflects key points from international consensus statements published by leading experts and suggests promising directions for future research. Expand
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TLDR
It is demonstrated that MINOCA was associated with a high risk of in-hospital mortality compared with MI-CAD in the super-aging society, Japan. Expand
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TLDR
It is critical to use multimodality imaging when treating patients with MINOCA to help determine the underlying etiology and rule out mimics ofMINOCA, so that therapies appropriate to the etiology can be provided. Expand
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TLDR
The aim is to provide clinicians with an "Ariadne's thread" according to the recent fourth universal definition of MI in order to not get lost in MINOCA's labyrinth. Expand
Clinical presentation and 3-year outcomes of patients with acute coronary syndromes and non-obstructive coronary arteries on angiography
TLDR
The prognosis of Patients with ACS INOCA was more favorable than that of patients with ACS OCAD; however, the differences diminished after adjustments for the initial clinical profiles. Expand
Myocardial infarction with non-obstructive coronary arteries (MINOCA): Intracoronary imaging-based diagnosis and management.
Myocardial infarction with non-obstructive coronary arteries (MINOCA) is defined by clinical evidence of myocardial infarction (MI) with normal or near-normal coronary arteries on angiography. ThisExpand
A pragmatic diagnostic approach to myocardial infarction with non-obstructive coronary arteries.
TLDR
By following a systematic approach of diagnostic tests, an underlying cause of MINOCA can be found in the majority of cases, allowing a directed management strategy to be pursued. Expand
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