Contaminants from the transplant contribute to intimal hyperplasia associated with microvascular endothelial cell seeding.


OBJECTIVES seeding prosthetic grafts with fat-derived microvascular endothelial cells (MVEC) results not only in a non-thrombogenic EC layer, but also in intimal hyperplasia. Here we investigated incidence, composition, progression, and cause of this intimal hyperplasia. DESIGN EPTFE grafts with MVEC were implanted as carotid interpositions in six dogs… (More)