Contact guidance on microfabricated substrata: the response of teleost fin mesenchyme cells to repeating topographical patterns.

  • Abbey Wood
  • Published 1988 in Journal of cell science


The mesenchymal tissue component of the teleost pectoral fin bud has been explanted onto microfabricated quartz discs containing patterns of regular grooves of dimensions similar to those encountered by contact-guided cells in the intact fin system. Computer-aided analysis of cell migration on five separate patterns, from 1.8 to 7.4 microns repeat spacing… (More)


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