Contact-dependent inhibition of growth in Escherichia coli.

  title={Contact-dependent inhibition of growth in Escherichia coli.},
  author={Stephanie K. Aoki and Rupinderjit Pamma and Aaron D. Hernday and Jessica E Bickham and Bruce Albert Braaten and David A. Low},
  volume={309 5738},
Bacteria have developed mechanisms to communicate and compete with each other for limited environmental resources. We found that certain Escherichia coli, including uropathogenic strains, contained a bacterial growth-inhibition system that uses direct cell-to-cell contact. Inhibition was conditional, dependent upon the growth state of the inhibitory cell and the pili expression state of the target cell. Both a large cell-surface protein designated Contact-dependent inhibitor A (CdiA) and two… CONTINUE READING
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