Contact allergy to cosmetics: causative ingredients

  title={Contact allergy to cosmetics: causative ingredients},
  author={Anton C. Groot},
  journal={Contact Dermatitis},
  • A. Groot
  • Published 1 July 1987
  • Medicine
  • Contact Dermatitis
Of 1781 patients with contact dermatitis seen during a period of 6 years (1981–1986), 75(4.2%) had allergy to cosmetic products. The face was most frequently affected. In many cases, the dermatitis was limited to the eyelids (18.7%) or the face (40.0%). skin care products (moisturizing and cleansing cream/lotion/milk/) and deodorants (6.8%). The ingredients most often responsible were fragrances (45.1%), followed by the preservative Kathon® CG (11.0%) and the emulsifier oleamidopropyl… 
Contact Allergies to Cosmetics: Testing with 52 Cosmetic Ingredients and Personal Products
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Contact allergy to cosmetics: testing with patients' own products
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The role of contact allergy in the spectrum of adverse effects caused by cosmetics and toiletries
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Facial Contact Dermatitis
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Contact Dermatitis Due to Local Cosmetics: A Study from Northern India
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Contact Dermatitis in Nail Cosmetics
Patients should be counselled to approach future nail cosmetic products and procedures with caution and careful attention to ingredients, regardless of whether or not it has a “hypoallergenic” label.
Adverse reactions to fragrances
Side‐effects of fragrance materials present in cosmetics are reviewed with emphasis on clinical aspects: epidemiology, type, of adverse reactions, clinical picture, diagnostic procedures, and the sensitizers.
Usefulness of Patch Testing With Patient's Own Products in the Diagnosis of Allergic Contact Dermatitis
It is essential to include patient's own products in the study of allergic contact eczema to make a correct diagnosis, as 3.81% of the patients would not have been correctly diagnosed if their own products had not been included in patch tests.


A five-year study of cosmetic reactions.
Contact allergy to bornelone
The patient was advised to discontinue the use of the cream; since then, no skin complaints have recurred for a period of more than 15 months.
Contact allergy to preservatives – II
To determine whether the prevalence of allergic reactions to certain preservatives warrants their inclusion in a routine series for patch testing, a tray of 14 preservatives was tested in 501 consecutive suspected contact dermatitis patients and Kathon CG® and alkyl trimethyl ammonium chloride only was found.
Allergy to perfumes from toilet soaps and detergents in patients with dermatitis.
Primary sensitization to perfumes may contribute to the continued high incidence of sensitivity to wood tars and balsams.
Contact allergy to preservatives (I)
results. The impression concerning PFR-2 and simultaneous test reactions to colophony/hydroabietyl alcohol, balsam of Peru and perfume mixture was thus confirmed. The background for the simultaneous
Kathon® CG: cosmetic allergy and patch test sensitization
These appear to be the first case reports of non‐occupational sensitization to Kathon CG, a preservative for cosmetics and toiletries containing, as active ingredients, 5‐chloro‐2‐methyl‐4‐isothiazolin‐3‐one.
Patch tests with fragrance materials and preservatives
Patients suspected of cosmetic allergy were patch tested with a series of 16 fragrance materials and 9 preservatives and for more of these substances gave positive reactions, the largest numbers of positive patch test reactions were seen to isocugenol, oak moss, geraniol, α‐amylcinnamic alcohol, and a mixture of α-amyl cinnamic aldehyde.
The repeated open application test (ROAT)
Repeated open application tests (ROATs) were performed with common ingredients of vehicles in 86 patients with contact dermatitis, finding that of the patients with a questionable (?+) patch test result, 44% were positive in ROATs.
Contact allergy to oleamidopropyl dimethylamine
Although these are the first domumented cases of contact allergy to oleamidopropyl dimethylamine, it is argued that hypersensitivity to this compound may not be rare.
Manual of Contact Dermatitis
Fregert'sManual of Contact Dermatitisis packed with useful information and is highly recommended as a primer for those learning dermatology and as a brief refresher text for the practicing clinician.