Contact allergy and medicinal herbs

  title={Contact allergy and medicinal herbs},
  author={Werner Aberer},
  journal={JDDG: Journal der Deutschen Dermatologischen Gesellschaft},
  • W. Aberer
  • Published 5 October 2007
  • Biology
  • JDDG: Journal der Deutschen Dermatologischen Gesellschaft
Herbal treatments are becoming increasingly popular, and are often used for internal as well as dermatological conditions, both externally as well as orally. The prevalence of contact sensitization against several plants especially of the Compositae family is quite high in Europe. Sensitization seems to occur relatively frequent with a few species such as arnica, elecampane and tea tree (oil), and occurs rarely with the majority. Testing for plant allergy is problematic because of the limited… 

Cosmeceutical Contact Dermatitis—Cautions To Herbals

Risks associated with use of cosmetics marketed as “natural” are emphasized and specific botanical allergens implicated in causing allergic contact dermatitis are reviewed.

Plant Allergen-Induced Contact Dermatitis.

The different clinical forms of contact dermatitis (photoinduced, irritative, and allergic form) are described and recent publications in the field of contact Dermatitis are highlighted.

Current Knowledge on Interactions of Plant Materials Traditionally Used in Skin Diseases in Poland and Ukraine with Human Skin Microbiota

The review aims to summarize the hitherto scientific data on plant-based topical preparations used in Poland and Ukraine and indicate future directions of the studies respecting recent developments in understanding the etiology of skin diseases.

Botanicals in Dermatology

According to the number and quality of clinical trials with botanicals, the best evidence exists for the treatment of inflammatory skin diseases, i.e. atopic dermatitis and psoriasis, but many more controlled clinical studies are needed to determine the efficacy and risks of plant-derived products in dermatology.

Herbs–Are they Safe Enough? An Overview

The article reviews the recent literature on the adverse effects of herbal remedies including the most widely sold herbal medicinal products, like liquorice, garlic, ginger, green tea, and turmeric, etc., and reinforces the safety aspect of herbal products, which are considered to be relatively safe by common people.

Assessment of Skin Photoallergy Risk in Cosmetics Containing Herbal Extract Ingredients

It is shown that Coptis, shikonin, or curcumin at 5% concentration in cosmetics could be applied safely without inducing contact allergic and photosensitive reactions on the skin.

Topically used herbal products for the treatment of hair loss: preclinical and clinical studies

Several electronic databases and hand-searched references were used to summarize current knowledge regarding topically used herbal products for the treatment of hair loss acquired on the basis of preclinical and clinical studies.

Allergic Contact Dermatitis Due to Tea Tree Oil.

Surveillance of suspected adverse reactions to herbal products used as laxatives

The total number of 26 ARs recorded in 8 years is limited; however, the an under-reporting effect cannot be excluded, and taking into account the seriousness of the reported ARs, the low number of reports does not represent a guarantee of safety.



Contact sensitization from Compositae‐containing herbal remedies and cosmetics

Sensitization seems to occur relatively frequently with a few species such as arnica and elecampane, and occurs rarely with the majority, especially the widely used German chamomile, and the risk of elicitation of dermatitis by using Compositae‐containing products in ComposItae‐sensitive individuals is by‐and‐large unknown.

Absence of contact sensitization to Aloe vera (L.) Burm. f.

Aloe vera use does not justify unrestrained promotion of Aloe products, as scientific studies investigating the claims on its constitutional effects are few in number, and the majority of them have been unable to diminish the intuitive scepticism against miracle cures.

The seamy side of natural medicines: contact sensitization to arnica (Arnica montana L.) and marigold (Calendula officinalis L.)

It is concluded that compositae allergy contributes significantly to the epidemiology of contact dermatitis and that sensitization to arnica and marigold cannot be assessed by testing with the Compositae or sesquiterpene mix alone.

[Sensitization to tea tree oil in Germany and Austria. A multicenter study of the German Contact Dermatitis Group].

  • C. PirkerB. Hausen P. Frosch
  • Medicine
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
  • 2003
The results show that tea tree oil is an important contact allergen for some centers, but considering the great regional differences in frequencies of sensitization its inclusion into the standard series is not recommended yet.

Active sensitization to elecampane by patch testing with a crude plant extract

During the past 3 years, 16 patients with suspected plant dermatitis of unknown origin were first patch tested with a series of 5 allergens derived from wellknown sensitizing plants, and the reaction observed could confidently be attributed to the 1% extract of elecampane of the Compositae family.

Compositae dermatitis in a Danish dermatology department in one year

To investigate the frequency of Compositae sensitivity, the recently‐developed sesquiterpene lactone mix (SL mix) was included in the standard patch lest series and both the SL mix and the Composite mix may be considered suitable for routine screening of compositae allergy.

Recurrent erythema nodosum associated with Echinacea herbal therapy.

A case of recurrent erythema nodosum that is temporally and perhaps causally associated with use of echinacea herbal therapy is reported, suggesting a definite stimulatory effect on the cellular immune system.

Sesquiterpene lactone mix is not an adequate screen for Compositae allergy

70 patients suspected or known to have contact allergy to Compositae were patch tested with 0.1% sesquiterpene lactone mix (SL mix) and individual Compositae oleoresins. There were no apparent cases

Anaphylaxis to camomile: clinical features and allergen cross‐reactivity

Medicinal remedies of plant origin became very popular in recent years, and allergic reactions to these are on the rise, accordingly. Camomile has been reported as a potential trigger of severe