Consumption of soy isoflavone enriched bread in men with prostate cancer is associated with reduced proinflammatory cytokines and immunosuppressive cells.

@article{Lesinski2015ConsumptionOS,
  title={Consumption of soy isoflavone enriched bread in men with prostate cancer is associated with reduced proinflammatory cytokines and immunosuppressive cells.},
  author={Gregory B. Lesinski and Patrick K Reville and Thomas A. Mace and Gregory S Young and Jennifer H Ahn-Jarvis and Jennifer M. Thomas-Ahner and Yael Vodovotz and Zeenath S Ameen and Elizabeth M. Grainger and Kenneth M Riedl and Steven J Schwartz and Steven K. Clinton},
  journal={Cancer prevention research},
  year={2015},
  volume={8 11},
  pages={1036-44}
}
We hypothesized that soy phytochemicals may have immunomodulatory properties that may affect prostate carcinogenesis and progression. A randomized, phase II trial was conducted in 32 patients with prostate cancer with asymptomatic biochemical recurrence but no measurable disease on standard staging studies. Patients were randomized to two slices of soy bread (34 mg isoflavones/slice) or soy bread containing almond powder daily as a source of β-glucosidase. Flow cytometry and bioplex assays were… CONTINUE READING
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