Consumption of imipenem correlates with beta-lactam resistance in Pseudomonas aeruginosa.

@article{Lepper2002ConsumptionOI,
  title={Consumption of imipenem correlates with beta-lactam resistance in Pseudomonas aeruginosa.},
  author={Philipp Moritz Lepper and Eberhard Grusa and Helga Reichl and Josef H{\"o}gel and Matthias Trautmann},
  journal={Antimicrobial agents and chemotherapy},
  year={2002},
  volume={46 9},
  pages={2920-5}
}
It is generally assumed that the antibiotic prescription policy of a hospital has a significant impact on bacterial resistance rates; however, few studies are available to support this concept with valid statistical data. During a 3-year period from 1997 to 2000, we monitored the consumption of beta-lactam and other antibiotics with known activity against Pseudomonas aeruginosa in a 600-bed community hospital. Monthly isolations of P. aeruginosa were assessed, and resistance rates were recorded… CONTINUE READING
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