Consumption of hydrolyzable tannins-rich pomegranate extract suppresses inflammation and joint damage in rheumatoid arthritis.

@article{Shukla2008ConsumptionOH,
  title={Consumption of hydrolyzable tannins-rich pomegranate extract suppresses inflammation and joint damage in rheumatoid arthritis.},
  author={Meenakshi Shukla and Kalpana Gupta and Zafar Rasheed and Khursheed A. Khan and Tariq M Haqqi},
  journal={Nutrition},
  year={2008},
  volume={24 7-8},
  pages={733-43}
}
OBJECTIVE Although consumption of dietary supplements containing pomegranate extract (POMx) by patients with arthritis is on the rise, the efficacy of such preparations in suppressing joint inflammation and damage is not known. The present study was designed to evaluate a standardized preparation of POMx using collagen-induced arthritis (CIA) in mice, a widely used animal model of rheumatoid arthritis. METHODS CIA-susceptible DBA/1 mice were fed POMx by gavage before and after immunization… CONTINUE READING
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