Consumption of Polyphenol-Rich Zingiber Zerumbet Rhizome Extracts Protects against the Breakdown of the Blood-Retinal Barrier and Retinal Inflammation Induced by Diabetes

@inproceedings{Tzeng2015ConsumptionOP,
  title={Consumption of Polyphenol-Rich Zingiber Zerumbet Rhizome Extracts Protects against the Breakdown of the Blood-Retinal Barrier and Retinal Inflammation Induced by Diabetes},
  author={T F Tzeng and Tang-Yao Hong and Yu-Cheng Tzeng and S F Liou and I. M. Liu},
  booktitle={Nutrients},
  year={2015}
}
The present study investigates the amelioration of diabetic retinopathy (DR) by Zingiber zerumbet rhizome ethanol extracts (ZZRext) in streptozotocin-induced diabetic rats (STZ-diabetic rats). ZZRext contains high phenolic and flavonoid contents. STZ-diabetic rats were treated orally with ZZRext (200, 300 mg/kg per day) for three months. Blood-retinal barrier (BRB) breakdown and increased vascular permeability were found in diabetic rats, with downregulation of occludin, and claudin-5. ZZRext… CONTINUE READING
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Ocular complications of diabetes mellitus.

World journal of diabetes • 2015
View 1 Excerpt

Epidemiological Issues in Diabetic Retinopathy

Middle East African journal of ophthalmology • 2013
View 1 Excerpt

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