Consumer product in vitro digestion model: Bioaccessibility of contaminants and its application in risk assessment.

@article{Brandon2006ConsumerPI,
  title={Consumer product in vitro digestion model: Bioaccessibility of contaminants and its application in risk assessment.},
  author={Esther F. A. Brandon and Agnes G. Oomen and Cathy J. M. Rompelberg and Carolien H M Versantvoort and Jacqueline G M van Engelen and Adrienne J A M Sips},
  journal={Regulatory toxicology and pharmacology : RTP},
  year={2006},
  volume={44 2},
  pages={161-71}
}
This paper describes the applicability of in vitro digestion models as a tool for consumer products in (ad hoc) risk assessment. In current risk assessment, oral bioavailability from a specific product is considered to be equal to bioavailability found in toxicity studies in which contaminants are usually ingested via liquids or food matrices. To become bioavailable, contaminants must first be released from the product during the digestion process (i.e. become bioaccessible). Contaminants in… CONTINUE READING

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