Construction of two vicinal quaternary carbons by asymmetric allylic alkylation: total synthesis of hyperolactone C and (-)-biyouyanagin A.

@article{Du2009ConstructionOT,
  title={Construction of two vicinal quaternary carbons by asymmetric allylic alkylation: total synthesis of hyperolactone C and (-)-biyouyanagin A.},
  author={C. Du and Liqi Li and Y. Li and Zhixiang Xie},
  journal={Angewandte Chemie},
  year={2009},
  volume={48 42},
  pages={
          7853-6
        }
}
  • C. Du, Liqi Li, +1 author Zhixiang Xie
  • Published 2009
  • Chemistry, Medicine
  • Angewandte Chemie
  • eral, the stereoselective construction of two vicinal quaternary carbon centers relys on substrate control. Only a few catalytic asymmetric C C bond-forming reactions have been useful for constructing all-carbon quaternary stereocenters. The catalytic asymmetric synthesis of two vicinal quaternary carbon centers with high diastereoselectivity and enantioselectivity remains a formidable challenge. Palladium-catalyzed asymmetric allylic alkylation (PdAAA) reactions, which were pioneered by Trost… CONTINUE READING
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