Construction of phospholamban antisense RNA recombinant adeno-associated virus vector and its effects in rat cardiomyocytes

Abstract

AbstractAim:To construct a recombinant adeno-associated virus (rAAV) vector containing gene encoding phospholamban antisense RNA (asPLB), and analyse its effect on expression of PLB, expression and activity of sarco-endoplasmic reticulum Ca2+-ATPase (SERCA), and the change of intracellular free Ca2+ concentration ([Ca2+]i) in rat cardiomyocytes.Methods:The… (More)
DOI: 10.1111/j.1745-7254.2005.00006.x

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@article{Li2005ConstructionOP, title={Construction of phospholamban antisense RNA recombinant adeno-associated virus vector and its effects in rat cardiomyocytes}, author={Jiang Li and Shen-jiang Hu and Jian Sun and Zhao-hui Zhu and Xia Zheng and Guo-zhong Wang and Yu-mei Yao and Nai-yun Chen and Xiao-Yan Zhao}, journal={Acta Pharmacologica Sinica}, year={2005}, volume={26}, pages={51-55} }