Construction of highly attenuated Salmonella enterica serovar Typhimurium live vectors for delivering heterologous antigens by chromosomal integration.


Attenuated live Salmonella enterica serovar Typhimurium is a versatile organism for the generation of live recombinant vaccines for mucosal immunization and various approaches were devised for the stable and efficient expressions of heterologous antigens by attenuated S. enterica strains. Phage lamda Red recombinase has recently been devised for gene… (More)


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