Construction of genetic network using evolutionary algorithm and combined fitness function.

  title={Construction of genetic network using evolutionary algorithm and combined fitness function.},
  author={Ando Shin and Hitoshi Iba},
  journal={Genome informatics. International Conference on Genome Informatics},
This paper proposes a method to capture the dynamics in gene expression data using S-system formalism and construct genetic network models. Our purposed method exploits the probabilistic heuristic search and divide-and-conquer approach to estimate the network structure. In evaluating the network structure, we attempt a primitive integration of other knowledge to the statistical criterion. The Z-score is used to analyze the robust and significant parameters from stochastic search results. We… CONTINUE READING
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