Construction of carbon nanotube based nanoarchitectures for selective impedimetric detection of cancer cells in whole blood.

@article{Liu2014ConstructionOC,
  title={Construction of carbon nanotube based nanoarchitectures for selective impedimetric detection of cancer cells in whole blood.},
  author={Yang Liu and Fanjiao Zhu and Wangxia Dan and Yu Fu and Shaoqin Liu},
  journal={The Analyst},
  year={2014},
  volume={139 20},
  pages={
          5086-92
        }
}
A carbon nanotube (CNT) based nanoarchitecture is developed for rapid, sensitive and specific detection of cancer cells by using real time electrical impedance sensing. The sensor is constructed with carbon nanotube (CNT) multilayers and EpCAM (epithelial cell adhesion molecule) antibodies, which are assembled on an indium tin oxide (ITO) electrode surface. The binding of tumor cells to EpCAM antibodies causes increase of the electron-transfer resistance. The electrochemical impedance of the… 
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32 Citations
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Methods Citations
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32 Citations

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The bioactive bent MWCNTs can play a significant role in ultrasensitive biosensors to improve their detection limit, thereby achieving early detection and monitoring of CRP-related diseases such as cardiovascular events and melanoma.
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