Construction of a versatile and functional nanoparticle platform derived from a helical diblock copolypeptide-based biomimetic polymer.

@article{Fan2014ConstructionOA,
  title={Construction of a versatile and functional nanoparticle platform derived from a helical diblock copolypeptide-based biomimetic polymer.},
  author={Jingwei Fan and Richen Li and Xun He and Kellie Seetho and Fuwu Zhang and Jiong Zou and Karen L Wooley},
  journal={Polymer chemistry},
  year={2014},
  volume={5 13},
  pages={
          3977-3981
        }
}
Sequential polymerization of N-carboxyanhydrides accelerated by nitrogen flow is utilized to generate a novel well-defined diblock copolypeptide (PDI = 1.08), with incorporation of alkyne-functionalized side-chain groups allowing for rapid and efficient thiol-yne click-type modifications, followed by self-assembly into nanopure water to construct a helical… CONTINUE READING