Construction of a junction DNA nanostructure and modulation of the junction switching to quadruplexes

Abstract

A junction DNA nanostructure has been successfully built in lithium acetate buffer solution at a near-neutral pH value through the connection of two slipped junction structures that are formed by G-rich and C-rich strands. The GC-rich duplex junctions in the nanostructure can be switched to G-quadruplexes and i-motifs in weakly acidic potassium acetate… (More)
DOI: 10.1098/rsos.171337

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